{"id":2186,"date":"2022-06-21T10:39:46","date_gmt":"2022-06-21T13:39:46","guid":{"rendered":"http:\/\/endocrinologiacuritiba.com.br\/?p=2186"},"modified":"2022-06-21T12:43:48","modified_gmt":"2022-06-21T15:43:48","slug":"endo-2021-criancas-com-diabetes-tipo-1-tem-maior-risco-de-complicacoes-por-covid-19","status":"publish","type":"post","link":"https:\/\/endocrinologiacuritiba.com.br\/blog\/portal-pebmed\/endo-2021-criancas-com-diabetes-tipo-1-tem-maior-risco-de-complicacoes-por-covid-19\/","title":{"rendered":"ENDO 2021: crian\u00e7as com diabetes tipo 1 t\u00eam maior risco de complica\u00e7\u00f5es por Covid-19?"},"content":{"rendered":"

\"seringa<\/p>\n

Desde o in\u00edcio da pandemia de Covid-19, estudos t\u00eam mostrado que adultos com diabetes tipo 1 e tipo 2 podem ter um maior risco de complica\u00e7\u00f5es e morte pela infec\u00e7\u00e3o. Entretanto, h\u00e1 poucos dados dispon\u00edveis sobre a rela\u00e7\u00e3o entre diabetes tipo 1 (DM1) e Covid-19 em crian\u00e7as e adolescentes.<\/p>\n

Covid-19 em crian\u00e7as com diabetes<\/span><\/strong><\/p>\n

\nEm busca desses dados, Manish Raisingani e Cols analisaram os dados do TriNetX, um banco de dados internacional que coleta dados de registros m\u00e9dicos eletr\u00f4nicos em tempo real de pacientes menores de 18 anos de 60 organiza\u00e7\u00f5es de sa\u00fade.<\/p>\n

Os autores compararam os dados de pacientes que foram diagnosticados com Covid-19, com e sem DM1, com rela\u00e7\u00e3o a complica\u00e7\u00f5es que inclu\u00edam intuba\u00e7\u00e3o, sepse e morte.<\/p>\n

Veja os dados mostrados pelo autor durante apresenta\u00e7\u00e3o virtual no ENDO 2021<\/strong> nas tabelas abaixo:<\/p>\n

Tabela 1. Mortalidade<\/strong><\/p>\n\n\n\n\n\n\n\n\n
Pacientes<\/td>\nSem diabetes tipo 1<\/td>\nTodos os pacientes com diabetes tipo 1<\/td>\nDM 1 com\u00a0
\nHbA1c \u2264 7%<\/td>\n<\/tr>\n
Total pacientes<\/td>\n502.655<\/td>\n3.047<\/td>\n482<\/td>\n<\/tr>\n
N\u00famero de \u00f3bitos<\/td>\n235<\/td>\n10<\/td>\n0<\/td>\n<\/tr>\n
Risco percentual<\/td>\n0,047<\/td>\n0.328<\/td>\n0<\/td>\n<\/tr>\n
Risco Relativo<\/td>\n1<\/td>\n7.04<\/td>\n0<\/td>\n<\/tr>\n
P<\/td>\n–<\/td>\n<0.0001<\/td>\n0.6349<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

 <\/p>\n

Tabela 2. Sepse<\/strong><\/p>\n\n\n\n\n\n\n\n\n
Pacientes<\/td>\nSem diabetes tipo 1<\/td>\nTodos os pacientes com diabetes tipo 1<\/td>\nDM 1 com\u00a0
\nHbA1c \u2264 7%<\/td>\n<\/tr>\n
Total pacientes<\/td>\n502.655<\/td>\n3.047<\/td>\n482<\/td>\n<\/tr>\n
N\u00famero c\/ sepsis<\/td>\n275<\/td>\n15<\/td>\n0<\/td>\n<\/tr>\n
Risco percentual<\/td>\n0.114<\/td>\n0.492<\/td>\n0<\/td>\n<\/tr>\n
Risco Relativo<\/td>\n1<\/td>\n4.32<\/td>\n0<\/td>\n<\/tr>\n
P<\/td>\n–<\/td>\n<0.0001<\/td>\n0.7913<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

 <\/p>\n

Tabela 3. Intuba\u00e7\u00e3o<\/strong><\/p>\n\n\n\n\n\n\n\n\n
Pacientes<\/td>\nSem diabetes tipo 1<\/td>\nTodos os pacientes com diabetes tipo 1<\/td>\nDM 1 com\u00a0
\nHbA1c \u2264 7%<\/td>\n<\/tr>\n
Total pacientes<\/td>\n502.655<\/td>\n3.047<\/td>\n482<\/td>\n<\/tr>\n
N\u00famero de intuba\u00e7\u00f5es<\/td>\n142<\/td>\n10<\/td>\n0<\/td>\n<\/tr>\n
Risco percentual<\/td>\n0.028<\/td>\n0.328<\/td>\n0<\/td>\n<\/tr>\n
Risco Relativo<\/td>\n1<\/td>\n11.65<\/td>\n0<\/td>\n<\/tr>\n
P<\/td>\n–<\/td>\n<0.0001<\/td>\n0.6614<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

 <\/p>\n

Conclus\u00f5es<\/strong><\/span><\/p>\n

\nOs autores conclu\u00edram que<\/strong>:<\/p>\n

    \n
  1. Crian\u00e7as com diabetes tipo 1 est\u00e3o sob maior risco de complica\u00e7\u00f5es por Covid-19.<\/li>\n
  2. Por outro lado, crian\u00e7as com diabetes tipo 1 bem controlado apresentam excelente evolu\u00e7\u00e3o com Covid-19, semelhante ao que se espera em crian\u00e7as sem DM1.<\/li>\n
  3. \u00c9 extremamente importante que a glicemia esteja bem controlada durante a pandemia para prevenir hospitaliza\u00e7\u00f5es e mortes em crian\u00e7as com diabetes tipo 1.<\/li>\n<\/ol>\n

     <\/p>\n

    Mais do congresso:<\/strong><\/p>\n

      \n
    • ENDO 2021: gerenciamento de precis\u00e3o dos efeitos end\u00f3crinos tardios em sobreviventes de c\u00e2ncer infantil<\/li>\n
    • ENDO 2021: s\u00edndrome dos ov\u00e1rios polic\u00edsticos na adolesc\u00eancia e em mulheres jovens<\/li>\n
    • ENDO 2021: como tratar osteoporose durante a pandemia de Covid-19?<\/li>\n
    • ENDO 2021: insufici\u00eancia adrenal como complica\u00e7\u00e3o da Covid-19<\/li>\n
    • ENDO 2021: vitamina D na preven\u00e7\u00e3o de diabetes tipo 2 \u2013 sim ou n\u00e3o?<\/li>\n
    • ENDO 2021: conectando-se \u00e0 tecnologia para um melhor atendimento ao paciente com diabetes<\/li>\n
    • ENDO 2021: o que \u00e9 a tireoidite at\u00edpica induzida por Covid-19?<\/li>\n
    • ENDO 2021: qual a rela\u00e7\u00e3o entre obesidade e Covid-19?<\/li>\n
    • ENDO 2021: como identificar e abordar a insufici\u00eancia adrenal no paciente cr\u00edtico?<\/li>\n
    • ENDO 2021: existe rela\u00e7\u00e3o entre sinaliza\u00e7\u00e3o androg\u00eanica e gravidade da Covid-19?<\/li>\n<\/ul>\n

       <\/p>\n

      Refer\u00eancias bibliogr\u00e1ficas:<\/strong><\/span><\/p>\n

        \n
      • Little Rock, AR. Risk of Complications in Children With Type 1 Diabetes and Covid-19. Manish Raisingani MD University of Arkansas for Medical Sciences. ENDO2021.<\/li>\n<\/ul>\n

         <\/p>\n

        Artigo publicado no Portal PEBMED em 29 Mar\u00e7o de 2021.<\/p>\n

         <\/p>\n

        Autora:\u00a0Daniele C. Tokars Zaninelli, endocrinologista em Curitiba.<\/strong><\/p>\n<\/div><\/div><\/div><\/div><\/div>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":2,"featured_media":2187,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_joinchat":[]},"categories":[27],"tags":[],"yoast_head":"\nENDO 2021: crian\u00e7as com diabetes tipo 1 t\u00eam maior risco de complica\u00e7\u00f5es por Covid-19? - Dra. 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